Signs of a severe allergic reaction include swelling of the face, lips, tongue, or throat, difficulty breathing, or a widespread rash with blistering. This is a medical emergency separate from the common, milder side effects described elsewhere in this library.
Severe allergic reaction
Though uncommon, any medication including trazodone can trigger a severe allergic reaction requiring emergency treatment.
Editorially reviewed
Key points
- Uncommon but possible with any medication
- Facial/throat swelling or breathing trouble is an emergency
Call your prescriber or seek care if you notice:
- Swelling of face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Widespread rash or hives with blistering
Not medical advice. This page describes general patterns reported for trazodone and does not replace individualized guidance from your prescriber or pharmacist.