Interestingly, trazodone's FDA labeling lists weight loss as a common side effect, which differs from many other antidepressants more associated with weight gain. Real-world experience varies by person, dose, and how trazodone affects appetite and sleep for that individual. Significant, unintentional weight change in either direction is worth mentioning to your prescriber.
Weight changes
Trazodone's label lists weight loss among common effects, though individual experience varies and some people report the opposite.
Editorially reviewed
Key points
- FDA labeling specifically lists weight loss as common
- Individual experience can vary
- Report significant unintentional weight change to your prescriber
Not medical advice. This page describes general patterns reported for trazodone and does not replace individualized guidance from your prescriber or pharmacist.