Common

Constipation

A commonly reported digestive side effect, generally manageable with fiber, fluids, and activity.

Editorially reviewed

Key points

Generally responds to fiber, fluids, and activity
Discuss persistent symptoms with a pharmacist or prescriber

Constipation is reported by some trazodone users and tends to respond to standard measures: adequate fluid intake, dietary fiber, and regular physical activity. Persistent constipation despite these measures is worth discussing with a prescriber or pharmacist, who may suggest a stool softener.

Not medical advice. This page describes general patterns reported for trazodone and does not replace individualized guidance from your prescriber or pharmacist.

Similar severity

Dry mouth

A common, usually mild anticholinergic-type effect that can be managed with hydration and sugar-free lozenges.

Dizziness and lightheadedness

A frequently reported effect linked to trazodone's impact on blood pressure regulation, especially when changing position quickly.

Nausea and vomiting

Reported by a meaningful share of trazodone users, particularly early in treatment, and often reduced by taking the dose with food.

Fatigue and tiredness

Distinct from acute drowsiness, this is a lingering sense of low energy some people notice, especially early in treatment.

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