Trazodone's prescribing information lists seizures among the most severe reactions reported specifically in overdose situations. Anyone who experiences a seizure — whether or not overdose is suspected — needs emergency medical attention. People with a seizure disorder should discuss this specifically with their prescriber, since some medications can lower the seizure threshold.
Seizures
Seizures are listed among the most severe reactions reported with trazodone overdose, and are a medical emergency wherever they occur.
Editorially reviewed
This can be a medical emergency. If you notice these signs in yourself or someone else, call 911 (US) or go to the nearest emergency room immediately. Do not wait to see if it passes.
Key points
- Listed among the most severe overdose reactions
- Any seizure requires emergency medical attention
- Discuss seizure history with your prescriber before starting
Call your prescriber or seek care if you notice:
- Any seizure activity
- Loss of consciousness with convulsions
Not medical advice. This page describes general patterns reported for trazodone and does not replace individualized guidance from your prescriber or pharmacist.