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Less common

Decreased libido

Changes in sexual desire are reported less often with trazodone than with SSRIs, though they can still occur.

Editorially reviewed
Key points
  • Generally less frequent than with SSRIs
  • Sometimes used to help offset another antidepressant's sexual side effects

Sexual side effects are generally reported less frequently with trazodone than with SSRIs, which is one reason it is sometimes used specifically to help offset sexual side effects from another antidepressant. Still, decreased libido can occur and should be discussed with a prescriber, since dose adjustment or another approach may help.

Not medical advice. This page describes general patterns reported for trazodone and does not replace individualized guidance from your prescriber or pharmacist.

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