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What withdrawal symptoms can happen if I stop trazodone suddenly?

Short answer: The FDA label specifically lists anxiety, agitation, and sleep problems as withdrawal symptoms associated with stopping trazodone.

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These symptoms reflect the nervous system readjusting after the medication's effects on serotonin and histamine activity are removed. Symptoms are generally more likely and more pronounced after higher doses or longer duration of use, which is why a gradual taper planned with your prescriber is the recommended approach rather than stopping cold.

Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.

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