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Does trazodone cause weight gain?

Short answer: Trazodone's FDA labeling actually lists weight loss, not weight gain, among common side effects — though individual experience varies, and some people do report the opposite.

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This surprises some people, since many antidepressants are more associated with weight gain. Trazodone's clinical trial data lists weight loss as a common effect, though real-world experience is individual — changes in appetite, sleep quality, and activity level while on any medication can all influence weight in either direction. Significant unintentional weight change should be discussed with your prescriber.

Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.

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