Not medical advice. General education only — not medical advice, and not a substitute for your prescriber or pharmacist. Emergency & crisis resources · How we review content

Does trazodone affect heart rhythm?

Short answer: It can affect the QT interval, particularly at higher doses or combined with other QT-affecting drugs. Mention any personal or family heart rhythm history before starting.

Editorially reviewed

See our QT prolongation side-effect page for detail. This is one of the more clinically important things to discuss before starting trazodone if you have any personal or family history of arrhythmia, unexplained fainting, or long QT syndrome.

Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.

Keep track of your own experience

The Medication Companion lets you log doses, sleep, symptoms, and questions for your prescriber — privately, in your browser, no account required to start.

Open the Medication Companion