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Medication Interaction Checklist for Trazodone

A printable worksheet to list every medication, supplement, and substance you use, to review with your prescriber or pharmacist for trazodone interactions.

Version dated August 8, 2026

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List every item, even ones you consider unrelated — prescription medications, over-the-counter drugs, vitamins, herbal supplements, and regular alcohol or cannabis use. For each, note the name, dose, and how often you use it.

Bring this list to your prescriber or pharmacist and specifically ask about serotonin syndrome risk (for other antidepressants, triptans, tramadol, or supplements like St. John's Wort or 5-HTP), and about CYP3A4 interactions (for certain antifungals, antibiotics, or seizure medications). See our full Interaction Library for details on specific combinations.