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Per FDA label

Trazodone with a personal or family history of heart rhythm problems

A personal or family history of QT prolongation, arrhythmia, or unexplained fainting is directly relevant to trazodone's labeled cardiac risk and should be discussed before starting.

Editorially reviewed
Key points
  • Directly relevant to trazodone's own labeled cardiac risk
  • Disclose personal and family cardiac history before starting
  • A baseline ECG may be appropriate in higher-risk situations

Because trazodone can affect the QT interval, anyone with a personal history of arrhythmia, unexplained fainting, or a family history of long QT syndrome or sudden cardiac events should discuss this specifically before starting trazodone. Prescribers may order a baseline ECG or choose a lower starting dose in these situations.

Not medical advice. Always tell your prescriber and pharmacist about every medication, supplement, and substance you use so they can check for interactions specific to your situation.

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