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Trazodone Before Surgery

What to tell your surgical and anesthesia team, and whether trazodone typically needs to be stopped before a procedure.

Editorially reviewed

Written by Trazodone.net Editorial Team, Editorial staff. 2 min read.

Key points
  • Always disclose trazodone use before any procedure with anesthesia
  • Relevant to sedation depth, blood pressure, and cardiac monitoring
  • Usually does not need to be stopped, but confirm with your care team

Always tell your surgical and anesthesia team that you take trazodone before any procedure involving anesthesia. Its sedative effect, influence on blood pressure, and potential QT-interval interaction with certain anesthesia medications are all relevant to how your care team plans monitoring during and after surgery.

In most cases, trazodone does not need to be stopped before surgery, but this should be explicitly confirmed with your surgical and prescribing teams rather than assumed — some procedures or planned medications may call for adjustment.

References

  1. Trazodone: MedlinePlus Drug Information. U.S. National Library of Medicine (MedlinePlus). View source (opens in a new tab) Accessed August 8, 2026
  2. Trazodone Hydrochloride Tablets — FDA Prescribing Information. DailyMed / U.S. Food & Drug Administration. View source (opens in a new tab) Accessed August 8, 2026
Not medical advice. This article is educational and does not replace guidance from your prescriber or pharmacist. If you think you're having a serious reaction, see our emergency resources page.

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